Eton Pharmaceuticals and Xellia Pharmaceuticals Announce Biorphen® (phenylephrine HCl) Co-Promotion Agreement
- Xellia’s US-based Hospital Sales Force Will Immediately Begin Promoting Biorphen in Collaboration with Eton
- Agreement Significantly Expands Biorphen Commercial Footprint and Provides Access to Institutions that Prefer Ready-to-Use Injectable Formulations
- Biorphen, the Only FDA-approved Formulation of Ready-to-Use Phenylephrine Injection, was Launched in
“We are excited to collaborate with Xellia on the promotion of Biorphen. Given our overlapping target markets, this agreement is a compelling opportunity for Eton to increase Biorphen’s commercial footprint and leverage Xellia’s established relationships with hospitals that have adopted ready-to-use injectable products,” said
“This is a great opportunity for us to work with Eton to co-promote Biorphen; the collaboration fits well with our overall mission to bring life-saving medicines that address unmet patients’ needs. Eton has a similarly bold company culture and focus to Xellia, which aligns with our ambition to bring more ready-to-use products to the US market where time is critical to the patient and in alignment to industry guidelines” said
Xellia’s hospital sales force will immediately begin promoting Biorphen in certain market segments in collaboration with Eton’s existing commercial team. The agreement significantly increases the number of sales representatives actively promoting Biorphen and provides Eton with immediate access to accounts that have already adopted Xellia’s
Biorphen® (phenylephrine HCI) Injection is the first and only
Indications and Usage
BIORPHEN injection is an alpha-1 adrenergic receptor agonist indicated for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia.
Important Safety Information
Warnings and Precautions: BIORPHEN can precipitate angina in patients with severe arteriosclerosis or history of angina, exacerbate underlying heart failure, and increase pulmonary arterial pressure. Can also cause excessive peripheral and visceral vasoconstriction and ischemia to vital organs. Extravasation during intravenous administration may cause necrosis or sloughing of tissue. Can cause severe bradycardia and decreased cardiac output, renal toxicity, augmented pressor effect in patients with autonomic dysfunction and pressor effect with concomitant oxytocic drugs.
Most common adverse reactions during treatment: nausea, vomiting, and headache.
To report SUSPECTED ADVERSE REACTIONS, contact
Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids.
Antagonistic Effects (decrease in BIORPHEN blood pressure effect) can occur with α-adrenergic antagonists, phosphodiesterase Type 5 inhibitors, mixed α- and β-receptor antagonists, calcium channel blockers, benzodiazepines and ACE inhibitors, centrally acting sympatholytic agents
Overdose of BIORPHEN (phenylephrine hydrochloride) can cause a rapid rise in blood pressure. Symptoms of overdose include headache, vomiting, hypertension, reflex bradycardia, a sensation of fullness in the head, tingling of the extremities, and cardiac arrhythmias including ventricular extrasystoles and ventricular tachycardia.
With over 100 years of experience, Xellia is a world-leading trusted supplier of several important established anti-infective drugs, comprising active pharmaceutical ingredients as well as injectable products. Continuing the Company’s evolution, Xellia is generating an innovative pipeline of value-added anti-infective medicines intended to enhance patient care, providing convenience and ease of use for healthcare professionals.
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Source: Eton Pharmaceuticals